Automating quality control, from bench to report.

We are building Sapho Bio as an automation-first lab, where robotic sample prep, an AI-built operations portal, and instrument-connected data come together to make release testing faster and more reliable.

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HOW WE DO IT

Speed and reliability in quality control come from designing the manual steps out of the process.

We’re automating the full lifecycle of a sample: the lab that prepares it, the record that captures it, the operations that move it, and the data that becomes the result.

Every layer de-risks and shortens the path from sample in to result out.

Automation is the obvious win for quality control testing. Reliability is much higher than with human operators, especially when you consider interhuman variance or the lag required to retrain an operator on new SOPs.

Speed and bandwidth are higher in the projects we choose to pursue. Compared to humans you lose some flexibility and adaptability, but that gap is shrinking in today’s physical intelligence wave.

Our north star is to automate the full lifecycle of a test from receiving the sample, performing the assay, recording the result, and compiling the certificate with full traceability at each step.

Speed and reliability in quality control come from designing the manual steps out of the process.

We’re automating the full lifecycle of a sample: the lab that prepares it, the record that captures it, the operations that move it, and the data that becomes the result.

Every layer de-risks and shortens the path from sample in to result out.

Speed and reliability in quality control come from designing the manual steps out of the process.

We’re automating the full lifecycle of a sample: the lab that prepares it, the record that captures it, the operations that move it, and the data that becomes the result.

Every layer de-risks and shortens the path from sample in to result out.

John McSpedon

CTO

One sample. One connected path.

AUTOMATED WET LAB

Robotic liquid handling, engineered into our methods

Our sample prep procedures are built with robotic liquid handling in mind. As the number of tests is rapidly increasing, moving to Opentrons systems to optimize and automate nucleic acid extraction, designing out the hands-on variability that makes manual prep slow and inconsistent becomes crucial.

As we extend this across the other testing workflows, more of the bench will run the same way every time, which is exactly what quality control depends on.

Opentrons automated liquid handling setup

Benchling workspace showing lab sample and result data

AI-ASSISTED SCIENCE

Our science lives on Benchling, and AI works on top of it

We run our science on Benchling, the R&D platform that keeps experiments, samples, and results in one connected system of record.

On top of that data, we are exploring how to put Benchling’s AI to work: surfacing relevant past runs, helping design and analyze experiments, and turning the work into documentation and reports. The more of our science that lives in one place, the more the AI can do with it.

In-house SOFTWARE Development, powered by AI

A client portal we design, build, and evolve with AI

We use AI to design, build, test, and iterate on our client portal at app.saphobio.com. It is the operational backbone of our company, designed to bring the whole lifecycle of a sample into one place so nothing falls through the cracks, with a clear owner at every step.

Building it with AI lets us move quickly, shape the portal around how our clients and our team actually work, and keep rapidly expanding what it covers using real user feedback - both paying customers, and internal users.

Chevron diagram showing the client portal workflow

APP.SAPHOBIO.COM / OPERATIONS

DATA Automation from Edge Hardware to Client

From instrument data toward one-click reporting

We are connecting our instruments directly to reporting, so data flows from the machine into a generated report instead of being retyped by hand. Where this is in place, a reviewed report is close to one click away, cutting transcription, reducing error, and shortening the path from raw signal to approved result. We are extending it across more of our instruments and assays.

REPORTING LAYER / 04

INSTRUMENT

RAW SIGNAL

DASHBOARD

STRUCTURED DATA

ONE-CLICK REPORT

REVIEW & APPROVE

WHY IT MATTERS